The "St. Jude Dream Adventures" campaign consisted of a temporary 360-degree installation at the hospital that "transported" the children to Cordoba and Talampaya Park in Argentina, Monkey Jungle in Florida and the Great Maya Reef in Mexico. In it, they experienced the locations' natural wonders -- from fossils to colorful sea-life to wily monkeys -- in real time. Expedia employees whose own lives had been affected by serious illneses were on location as personal tour guides to show the kids the sites.

In one "adventure," a girl in love with horses watches them speed across Argentine plains with Expedia employee Sara L., a brain tumor survivor. Chera, whose family members have been diagnosed with cancer, leads a boy on a monkey adventure and Expedia employee Reenie, who also has family affected by cancer, goes scuba diving in Mexico to lead the underwater tour for Hannah, who has since passed away.